Midazolam & Seizures Essay Example | Topics and Well Written Essays - 250 words

midazolam & Seizures - Essay ExampleMidozolam increases the activity of gamma aminobutyric acid which gives a calming effect to the user. It also relaxes the skeletal muscles and result in sleep. The chemical in the practice of medicine called benzodiazepines bind to the receptors of GABA which enhances the effect of GABA by increasing the frequency of chloride channel opening.According to (Silver,1994,pg 350-60) Midazolam is a potent imidazobenzodiazepine used as a premedicant and as an anesthetic induction Agent.Midazolam is promising an agonist at both BZ1 and BZ2 receptors. Its performance at PBRs is not certain. The quick encephalopathic effects ofmidazolam may be connected to the trizolam like potency and lipophilicity of midazolam. Which are greatest among thebenzodizepines. Midazolam may also exert nearly anticholinergic activity.Silver, T, 1994. SCIENTIFIC ARTICLE Evaluation of two dosages of oral midazolam as a witting sedation for physically and neurologically compromis ed pediatric dental patients. Pediatric Dentistry, 16/5,